epitope library

epitope library
Large collection (hundreds of millions) of peptides each encoded by a randomly mutated piece of DNA in a phage genome and expressed on the surface of that bacteriophage, sometimes as an N-terminal extension of a coat protein. Particular phages can be selected by a binding assay and since the peptide has its encoding DNA associated with it sequencing is straightforward.

Dictionary of molecular biology. 2004.

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